Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241356 | 0.80 | CHRM3 (0.44) | CYP2D6MEN1KMT2ANAMPTMAPK1 | |
| SCHEMBL31374623 | 0.79 | NAMPT (0.42) | MEN1KMT2ANAMPTHDAC8MAPK1 | |
| SCHEMBL29029874 | 0.79 | NAMPT (0.42) | MEN1KMT2ANAMPTHDAC8MAPK1 | |
| SCHEMBL31070631 | 0.78 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL28242076 | 0.75 | TRPM8 (0.48) | MEN1KMT2ANAMPTMAPK1TRPM8 | |
| SCHEMBL31070488 | 0.75 | MEN1 (0.39) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL29029881 | 0.73 | GPR119 (0.43) | MEN1KMT2ANAMPTMAPK1TRPM8 | |
| SCHEMBL31444544 | 0.73 | MEN1 (0.42) | MEN1KMT2ANAMPTHDAC8MAPK1 | |
| SCHEMBL31444546 | 0.73 | MEN1 (0.42) | MEN1KMT2ANAMPTHDAC8MAPK1 | |
| SCHEMBL31374600 | 0.73 | HDAC8 (0.45) | MEN1KMT2ANAMPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |