Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593259 | 0.89 | CD274 (0.51) | MIFGSK3BGSK3ACD274SYK | |
| SCHEMBL25404671 | 0.89 | CD274 (0.51) | MIFGSK3BGSK3ACD274SYK | |
| SCHEMBL11548879 | 0.71 | MIF (0.48) | MIFGSK3BCHRM2CHRM4CHRM5 | |
| SCHEMBL31070511 | 0.71 | NR4A2 (0.53) | PDGFRB | |
| SCHEMBL31083760 | 0.71 | CD274 (0.53) | GSK3BGSK3ACD274 | |
| SCHEMBL25406535 | 0.71 | CD274 (0.53) | GSK3BGSK3ACD274 | |
| SCHEMBL1310425 | 0.70 | PIN1 (0.56) | MIFCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2490828 | 0.70 | CHRM2 (0.50) | MIFGSK3BCHRM2CHRM4CHRM5 | |
| SCHEMBL31070627 | 0.70 | ERN1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29543520 | 0.69 | PTPRC (0.46) | CD274PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |