Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 14/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401778 | 0.88 | CD274 (0.52) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL17096911 | 0.81 | TDO2 (0.56) | TDO2 | |
| SCHEMBL28377762 | 0.77 | NR4A2 (0.81) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL28416622 | 0.75 | NR4A2 (0.78) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL28129193 | 0.74 | HSD17B10 (0.51) | NR4A2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL20837488 | 0.74 | IMPDH2 (0.51) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL29713619 | 0.73 | TDO2 (0.70) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL18843523 | 0.72 | NR4A2 (0.57) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| SCHEMBL17114123 | 0.72 | TDO2 (0.49) | NR4A2TDO2IMPDH2MAPK1HSD17B10 | |
| 3-Phenylindole SCHEMBL84056 | 0.72 | IMPDH2 (0.71) | NR4A2TDO2IMPDH2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |