Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071826 | 0.89 | RET (0.45) | RETHDAC1KCNK3KCNK9 | |
| SCHEMBL31071779 | 0.89 | RET (0.45) | RETHDAC1KCNK3KCNK9 | |
| SCHEMBL31071808 | 0.86 | RET (0.66) | RET | |
| SCHEMBL31071888 | 0.84 | RET (0.54) | RET | |
| SCHEMBL28462137 | 0.84 | RET (0.54) | RET | |
| SCHEMBL28936733 | 0.81 | HDAC1 (0.47) | RETHDAC1KCNK3KCNK9 | |
| SCHEMBL31143957 | 0.77 | RET (0.54) | RET | |
| SCHEMBL28716631 | 0.77 | RET (0.54) | RET | |
| SCHEMBL31071775 | 0.77 | RET (0.56) | RET | |
| SCHEMBL31071857 | 0.75 | POLB (0.49) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777593-B | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |