Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969764 | 0.89 | HSD17B10 (0.45) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL26547640 | 0.88 | HSD17B10 (0.45) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6338610 | 0.86 | ATM (0.43) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29036991 | 0.86 | ATM (0.48) | ATMHSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29039235 | 0.86 | SMN1; SMN2 (0.41) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29039237 | 0.86 | SMN1; SMN2 (0.41) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6347276 | 0.85 | ATM (0.43) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6348716 | 0.84 | ATM (0.43) | ATMHSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6340488 | 0.84 | ATM (0.42) | ATMHSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26547634 | 0.84 | ATM (0.42) | ATMHSD17B10SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |