SCHEMBL31072244

SCHEMBL31072244

Brc1ccccc1-n1cnc2cccc(Br)c21

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR1 Q9BXC0 3/20 0.53
FGFR1 P11362 5/20 0.44
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MGLL Q99685 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5937 0.80 HTT (0.56) HCAR1FGFR1HTTPOLB
SCHEMBL29898298 0.80 HTT (0.56) HCAR1FGFR1HTTPOLB
SCHEMBL21113766 0.78 ALDH1A1 (0.50) FGFR1HTTMEN1KMT2APOLB
SCHEMBL9981015 0.72 DPP4 (0.41) FGFR1HTTMEN1KMT2A
SCHEMBL32675832 0.71 FGFR1 (0.44) FGFR1HTT
SCHEMBL2039172 0.70 FGFR1 (0.42) FGFR1HTTPOLB
SCHEMBL3950887 0.70 ALDH1A1 (0.44) FGFR1HTTPOLB
SCHEMBL24179153 0.70 FGFR1 (0.51) HCAR1FGFR1HTTPOLB
SCHEMBL2036673 0.70 HCAR1 (0.44) HCAR1FGFR1
SCHEMBL22188457 0.69 HTT (0.56) FGFR1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112341498-B Organic electroluminescent material and device 环球展览公司 2024-09-10 CN disclosed