Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073297 | 1.00 | TYR (0.48) | TYRALDH1A3ALDH1A1CYP2A6ADRB2 | |
| SCHEMBL8807193 | 1.00 | TYR (0.48) | TYRALDH1A3ALDH1A1CYP2A6ADRB2 | |
| SCHEMBL19812419 | 0.88 | TYR (0.38) | TYRALDH1A3ALDH1A1CYP2A6GRIA4 | |
| SCHEMBL9348331 | 0.83 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10823122 | 0.82 | TYR (0.55) | TYRALDH1A3ALDH1A1CYP2A6GRIA4 | |
| SCHEMBL6124172 | 0.80 | TYR (0.41) | TYRALDH1A3ALDH1A1CYP2A6ADRB2 | |
| SCHEMBL2902173 | 0.78 | KCNJ1 (0.31) | — | |
| SCHEMBL19822824 | 0.78 | TYR (0.31) | TYRKDM4E | |
| SCHEMBL20303038 | 0.78 | PPARG (0.40) | TYRALDH1A3ALDH1A1KDM4ELMNA | |
| SCHEMBL1985326 | 0.78 | ALDH1A3 (0.54) | TYRALDH1A3ALDH1A1CYP2A6ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |