Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408604 | 1.00 | APLNR (0.42) | APLNRCYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL31042359 | 1.00 | APLNR (0.42) | APLNRCYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL7365019 | 0.82 | APLNR (0.46) | APLNRCYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL21556841 | 0.81 | APLNR (0.31) | APLNR | |
| SCHEMBL26125642 | 0.81 | NPC1 (0.33) | APLNRALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL26125646 | 0.81 | NPC1 (0.33) | APLNRALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL3049989 | 0.81 | APLNR (0.39) | APLNRCYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL9185287 | 0.81 | ADRA2B (0.38) | ALDH1A1CYP2D6 | |
| SCHEMBL24010070 | 0.80 | APLNR (0.41) | APLNRALDH1A1 | |
| SCHEMBL6160560 | 0.80 | APLNR (0.41) | APLNRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |