Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.38 |
| ▸ | GCKR | Q14397 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 6/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073259 | 0.83 | MAPT (0.49) | GPR119 | |
| SCHEMBL31073137 | 0.83 | GCK (0.37) | GCKGCKRGPR119TRPC6AOC3 | |
| SCHEMBL31073352 | 0.82 | TRPC6 (0.39) | GCKGCKRTRPC6AOC3DHFR | |
| SCHEMBL31073262 | 0.82 | HRH3 (0.36) | GPR119AOC3HRH3 | |
| SCHEMBL31073285 | 0.82 | GCK (0.38) | GCKGCKRAOC3DHFRHRH3 | |
| SCHEMBL31073153 | 0.81 | DHFR (0.34) | GCKGCKRGPR119TRPC6AOC3 | |
| SCHEMBL31073239 | 0.81 | DRD4 (0.40) | GCKGCKR | |
| SCHEMBL31073273 | 0.80 | USP14 (0.33) | GCKGCKRGPR119USP14 | |
| SCHEMBL31072986 | 0.79 | KCNH2 (0.41) | HRH3 | |
| SCHEMBL31073006 | 0.79 | HRH3 (0.38) | GCKGCKRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |