Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073650 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10LMNAPLA2G1B | |
| SCHEMBL31073656 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10LMNAPLA2G1B | |
| SCHEMBL5963776 | 0.71 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL27327254 | 0.71 | MAPT (0.54) | KDM4EALDH1A1LMNAPOLBHSD17B2 | |
| SCHEMBL27331749 | 0.71 | HPGD (0.53) | KDM4EALDH1A1HSD17B10LMNAHSD17B2 | |
| SCHEMBL24221656 | 0.71 | SLC2A1 (0.67) | POLBHSD17B2 | |
| SCHEMBL5964006 | 0.71 | ADRB3 (0.62) | — | |
| SCHEMBL27327673 | 0.70 | HSD17B2 (0.50) | KDM4EALDH1A1HSD17B10HSD17B2MAPT | |
| SCHEMBL917709 | 0.69 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10LMNAPLA2G1B | |
| SCHEMBL27327251 | 0.69 | MAPT (0.45) | KDM4EALDH1A1HSD17B10LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173715-A1 | ANTIFUNGAL COMPOSITIONS AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-08-22 | — | — | WO | claimed |