Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964603 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10NPSR1HTT | |
| SCHEMBL2298222 | 0.74 | ADRB2 (0.64) | KDM4EL3MBTL1ADRB2ADRB3ADRB1 | |
| SCHEMBL2292601 | 0.74 | ADRB2 (0.64) | KDM4EL3MBTL1ADRB2ADRB3ADRB1 | |
| SCHEMBL5963771 | 0.73 | MEN1 (0.46) | ALDH1A1KDM4EHSD17B10NPSR1HTT | |
| SCHEMBL6767270 | 0.73 | KMT2A (0.59) | KDM4ENPSR1HTTMAPTHPGD | |
| SCHEMBL31073648 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10NPSR1HTT | |
| SCHEMBL31073656 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10NPSR1HTT | |
| SCHEMBL31073650 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10NPSR1HTT | |
| SCHEMBL5964006 | 0.70 | ADRB3 (0.62) | ADRB2ADRB3ADRB1 | |
| SCHEMBL5964144 | 0.69 | ADRB3 (0.56) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052315-A1 | Cb 1/cb 2 receptor ligands and their use in the treatment of pain | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | US | claimed |
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052315-A1 | Cb 1/cb 2 receptor ligands and their use in the treatment of pain | CNR1, CNR2, OPRL1 | ALDH1A1 806/4885KDM4E 3936/4885HSD17B10 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.