SCHEMBL3107397

SCHEMBL3107397

CC(C)(C)c1cc(F)ccc1OCC1CN(C(=O)CC(=O)O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 16/20 1.00
TTR P02766 3/20 0.46
CHRNA7 P36544 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.40
MGLL Q99685 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3105730 0.92 RBP4 (1.00) RBP4TTRMGLL
SCHEMBL3512157 0.90 RBP4 (0.82) RBP4TTRCHRNA7PTGDR2MGLL
SCHEMBL3109911 0.89 RBP4 (0.88) RBP4TTRMGLL
SCHEMBL3116476 0.87 RBP4 (0.78) RBP4TTRCHRNA7PTGDR2MGLL
SCHEMBL3111874 0.87 RBP4 (0.77) RBP4TTRCHRNA7MGLL
SCHEMBL3108209 0.87 RBP4 (0.78) RBP4
SCHEMBL3094516 0.86 RBP4 (0.83) RBP4TTR
SCHEMBL3100483 0.86 RBP4 (0.76) RBP4TTRCHRNA7
SCHEMBL13034538 0.84 RBP4 (0.73) RBP4TTRCHRNA7MGLL
SCHEMBL3107322 0.84 RBP4 (0.81) RBP4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US claimed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 CN claimed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 EP claimed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US claimed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP claimed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 CN claimed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 WO claimed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 WO claimed
EP-2202223-B1 HETEROCYCLIC COMPOUND AS BLOOD RBP4 LOWERING AGENT TAKEDA PHARMACEUTICALS CO (JP) 2017-01-25 EP claimed
US-8586571-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-11-19 US claimed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US claimed
EP-2202223-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2010-06-30 EP claimed
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US disclosed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 CN disclosed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 EP disclosed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
EP-2202223-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION PDE6C, SERPINA6, PDE6H RBP4 11/4885TTR 26/4885CHRNA7 612/4885
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION AGER, RBP4, RBP1 RBP4 2/4885TTR 178/4885CHRNA7 4496/4885
US-20100292206-A1 HETEROCYCLIC COMPOUND RBP4, RBP1, RAVER1 RBP4 1/4885TTR 460/4885CHRNA7 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.