SCHEMBL28008252

SCHEMBL28008252

CCOC(=O)C(C)c1ccccc1C(C)C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 3/20 0.50
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
PIN1 Q13526 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 1/20 0.45
GAA P10253 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
LPAR1 Q92633 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MMP8 P22894 1/20 0.42
CASP1 P29466 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363983 0.87 TSHR (0.48) NLRP3TSHRMAPK1PIN1SMN1; SMN2
SCHEMBL1044283 0.85 NLRP3 (0.50) NLRP3TSHRMAPK1PIN1SMN1; SMN2
SCHEMBL5598897 0.84 CA1 (0.57) NLRP3TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL16713579 0.84 TSHR (0.43) NLRP3TSHRPIN1SMN1; SMN2LMNA
SCHEMBL10858287 0.84 TSHR (0.53) NLRP3TSHRPIN1SMN1; SMN2LMNA
SCHEMBL5915141 0.84 NLRP3 (0.49) NLRP3TSHRMAPK1PIN1SMN1; SMN2
SCHEMBL31074064 0.84 TSHR (0.53) NLRP3TSHRPIN1SMN1; SMN2LMNA
SCHEMBL28008699 0.84 TSHR (0.46) NLRP3TSHRPIN1SMN1; SMN2LMNA
SCHEMBL16673225 0.82 TDP1 (0.51) TSHRPIN1SMN1; SMN2LMNAKMT2A
SCHEMBL10708969 0.82 CASP1 (0.57) NLRP3TSHRPIN1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104412441-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2015-03-11 CN disclosed