SCHEMBL31074282

SCHEMBL31074282

C=CCO[C@H]1C[C@H](n2cc(I)c(=O)[nH]c2=O)O[C@@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.42
BCHE P06276 4/20 0.41
RNASE1 P07998 1/20 0.40
TOP2A P11388 6/20 0.39
TYMS P04818 1/20 0.37
TK2 O00142 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23734172 0.87 TOP2A (0.49) TK1BCHETOP2A
SCHEMBL2120424 0.87 TOP2A (0.49) TK1BCHETOP2A
SCHEMBL2120421 0.87 TOP2A (0.49) TK1BCHETOP2A
SCHEMBL12047355 0.87 TOP2A (0.49) TK1BCHETOP2A
SCHEMBL27914580 0.85 RNASE1 (0.43) TK1BCHERNASE1TOP2ATYMS
SCHEMBL1335300 0.85 RNASE1 (0.43) TK1BCHERNASE1TOP2ATYMS
SCHEMBL1335302 0.85 RNASE1 (0.43) TK1BCHERNASE1TOP2ATYMS
SCHEMBL22977550 0.85 TK1 (0.58) TK1BCHETYMS
SCHEMBL20810641 0.85 TK1 (0.58) TK1BCHETYMS
SCHEMBL31074312 0.81 RNASE1 (0.36) RNASE1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642931-A1 METHODS OF SEQUENCING USING 3´ ALLYL BLOCKED NUCLEOTIDES Illumina, Inc. (US) 2025-11-05 EP disclosed
CN-119095984-A Sequencing methods using 3' allyl-terminated nucleotides 伊路米纳有限公司 2024-12-06 CN disclosed
WO-2024145154-A1 METHODS OF SEQUENCING USING 3´ ALLYL BLOCKED NUCLEOTIDES ILLUMINA, INC. (US) 2024-07-04 WO disclosed