Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.60 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.60 |
| ▸ | GPX4 | P36969 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31074289 | 0.84 | GPX4 (0.66) | FNIP1FEM1BGPX4ALDH1A1PKM | |
| SCHEMBL31074311 | 0.83 | GPX4 (0.69) | FNIP1FEM1BGPX4ALDH1A1MAPT | |
| SCHEMBL7341997 | 0.77 | NPC1 (0.71) | ALDH1A1MAPTNPC1RAB9AHTT | |
| SCHEMBL31074323 | 0.77 | GPX4 (0.77) | FNIP1FEM1BGPX4ALDH1A1PKM | |
| SCHEMBL23804991 | 0.75 | FNIP1 (1.00) | FNIP1FEM1BGPX4ALDH1A1MAPT | |
| SCHEMBL31074299 | 0.75 | GPX4 (0.81) | FNIP1FEM1BGPX4ALDH1A1MAPT | |
| SCHEMBL31074326 | 0.75 | GPX4 (0.74) | FNIP1FEM1BGPX4ALDH1A1MAPT | |
| SCHEMBL31074332 | 0.75 | GPX4 (0.71) | FNIP1FEM1BGPX4ALDH1A1PKM | |
| SCHEMBL31074320 | 0.74 | GPX4 (1.00) | FNIP1FEM1BGPX4ALDH1A1MAPT | |
| SCHEMBL16892952 | 0.72 | GPX4 (0.51) | FNIP1FEM1BGPX4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960073-B | N-halogenated acetyl diphenylamine derivative and preparation method and medical application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | disclosed |