Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072391 | 0.75 | SLC9A1 (0.60) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL10864544 | 0.74 | MAPT (0.95) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL28246810 | 0.74 | POLB (0.95) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL4459864 | 0.74 | SLC9A1 (0.54) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL1151656 | 0.74 | SLC9A1 (0.95) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL9171873 | 0.74 | SLC9A1 (0.54) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL9172879 | 0.74 | SLC9A1 (0.54) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL18372356 | 0.71 | SLC9A1 (0.56) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL3672275 | 0.71 | POLB (1.00) | SLC9A1MAPTPOLBMAPK1ATM | |
| SCHEMBL15548600 | 0.71 | SLC9A1 (0.56) | SLC9A1MAPTPOLBMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | SLC9A1 882/4885MAPT 4724/4885POLB 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.