Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075254 | 0.85 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL19224705 | 0.84 | AR (0.46) | MEN1KMT2A | |
| SCHEMBL19228569 | 0.79 | CACNA1H (0.41) | MEN1KMT2A | |
| SCHEMBL31075214 | 0.77 | ALDH1A1 (0.55) | KLKB1 | |
| SCHEMBL16891601 | 0.75 | PARP1 (0.47) | KLKB1 | |
| SCHEMBL16487173 | 0.74 | GAA (0.58) | KLKB1MEN1KMT2A | |
| SCHEMBL21190075 | 0.73 | GAA (0.51) | KLKB1 | |
| SCHEMBL31075184 | 0.72 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL17784845 | 0.72 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL9752787 | 0.71 | POLB (0.63) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665330-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173196-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |