SCHEMBL31076459

SCHEMBL31076459

CC(C)(C)OC(=O)N[C@H]1C[C@H]2CC[C@@H]1N2Cc1ccc(N2CCC(CF)CC2)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
DRD2 P14416 5/20 0.38
DRD3 P35462 2/20 0.38
SLC6A4 P31645 3/20 0.35
SLC6A3 Q01959 2/20 0.35
CCR3 P51677 1/20 0.35
NPY2R P49146 1/20 0.35
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31076450 0.84 KMT2A (0.44) KMT2AL3MBTL1DRD2DRD3CCR3
SCHEMBL31076346 0.83 KMT2A (0.49) KMT2AL3MBTL1DRD2DRD3SLC6A4
SCHEMBL24975769 0.78 L3MBTL1 (0.53) KMT2AL3MBTL1SLC6A4MEN1
SCHEMBL24976021 0.78 L3MBTL1 (0.53) KMT2AL3MBTL1SLC6A4MEN1
SCHEMBL24977220 0.78 L3MBTL1 (0.53) KMT2AL3MBTL1SLC6A4MEN1
SCHEMBL31076412 0.78 CYP2D6 (0.43) KMT2AL3MBTL1CCR3
SCHEMBL31076278 0.77 KMT2A (0.48) KMT2AL3MBTL1SLC6A4SLC6A3MEN1
SCHEMBL31076350 0.75 KMT2A (0.43) KMT2AL3MBTL1DRD2DRD3SLC6A4
SCHEMBL31076540 0.73 KMT2A (0.43) KMT2AL3MBTL1DRD2DRD3SLC6A3
SCHEMBL31076435 0.72 KMT2A (0.47) KMT2AL3MBTL1DRD2DRD3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642778-A1 LSD1 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
WO-2024141757-A1 LSD1 MODULATORS EXSCIENTIA AI LIMITED (GB) 2024-07-04 WO disclosed