Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976021 | 1.00 | L3MBTL1 (0.53) | L3MBTL1KMT2ACYP3A4ALDH1A1LTA4H | |
| SCHEMBL24977220 | 1.00 | L3MBTL1 (0.53) | L3MBTL1KMT2ACYP3A4ALDH1A1LTA4H | |
| SCHEMBL31076346 | 0.83 | KMT2A (0.49) | L3MBTL1KMT2AMEN1SLC6A4 | |
| SCHEMBL31076278 | 0.82 | KMT2A (0.48) | L3MBTL1KMT2AKDM1AMEN1SLC6A4 | |
| SCHEMBL24976392 | 0.82 | STS (0.49) | L3MBTL1KMT2AALDH1A1KDM1AMEN1 | |
| SCHEMBL24975772 | 0.81 | L3MBTL1 (0.47) | L3MBTL1KMT2ACYP3A4ALDH1A1LTA4H | |
| SCHEMBL31076459 | 0.78 | KMT2A (0.44) | L3MBTL1KMT2AMEN1SLC6A4 | |
| SCHEMBL29950234 | 0.78 | ALDH1A1 (0.47) | L3MBTL1CYP3A4ALDH1A1LTA4HCXCR4 | |
| SCHEMBL24977312 | 0.78 | ALDH1A1 (0.47) | L3MBTL1CYP3A4ALDH1A1LTA4HCXCR4 | |
| SCHEMBL31045844 | 0.77 | KMT2A (0.62) | L3MBTL1KMT2AKDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | AMGEN INC. (US) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | L3MBTL1 4695/4885KMT2A 2971/4885CYP3A4 432/4885 |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | CYP3A7, CYP51A1, NT5C3B | L3MBTL1 4695/4885KMT2A 2971/4885CYP3A4 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.