Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060380 | 0.77 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1TNIKRIPK1EGLN2 | |
| SCHEMBL30500187 | 0.76 | TNIK (0.40) | TNIKRIPK1MAP4K4EGLN2 | |
| SCHEMBL31078548 | 0.76 | PTGS2 (0.43) | TNIKRIPK1MAP4K4 | |
| SCHEMBL31078253 | 0.73 | PIK3CD (0.54) | CSNK2A2CSNK2A1PIK3CD | |
| SCHEMBL20820178 | 0.72 | MAP4K4 (0.47) | TNIKRIPK1MAP4K4 | |
| SCHEMBL90896 | 0.72 | TNIK (0.37) | CSNK2A2CSNK2A1TNIKRIPK1MAP4K4 | |
| SCHEMBL14313224 | 0.71 | RIPK1 (0.52) | PIK3CDTNIKRIPK1 | |
| SCHEMBL15740086 | 0.71 | MAP4K4 (0.46) | PIK3CDTNIKRIPK1MAP4K4EGLN2 | |
| SCHEMBL23143384 | 0.70 | SMN1; SMN2 (0.66) | EGLN2 | |
| SCHEMBL19690100 | 0.70 | RIPK1 (0.62) | CSNK2A2CSNK2A1PIK3CDTNIKRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |