Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078505 | 0.87 | HTR1B (0.49) | KMT2APOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL31078661 | 0.78 | ALDH1A1 (0.51) | POLBKDM4EALDH1A1MAPTHTT | |
| SCHEMBL3076860 | 0.75 | KMT2A (0.46) | KMT2APOLBKDM4ELMNAMEN1 | |
| SCHEMBL3989280 | 0.74 | POLB (0.63) | KMT2APOLBKDM4EALDH1A1MAOB | |
| SCHEMBL3007594 | 0.73 | GAA (0.71) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8338047 | 0.72 | ALDH1A1 (0.66) | KMT2APOLBKDM4EALDH1A1MAPT | |
| SCHEMBL4897162 | 0.72 | KDR (0.54) | KMT2APOLBKDM4EALDH1A1MAPT | |
| SCHEMBL4708254 | 0.72 | GAA (0.51) | KMT2APOLBKDM4EALDH1A1MAPT | |
| SCHEMBL2788543 | 0.72 | CNR1 (0.72) | POLBKDM4EMAOBCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL14742324 | 0.72 | GAA (0.70) | KMT2AKDM4ELMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |