Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379773 | 0.81 | KMT2A (0.68) | KMT2AL3MBTL1RAB9AMEN1CYP1A2 | |
| SCHEMBL4698700 | 0.75 | IKBKB (0.46) | KMT2AMEN1CYP1A2ALDH1A1PKM | |
| SCHEMBL16336026 | 0.75 | L3MBTL1 (0.61) | KMT2AL3MBTL1RAB9AMEN1CYP1A2 | |
| SCHEMBL14342685 | 0.73 | BCAT2 (0.47) | KMT2AL3MBTL1MEN1CYP1A2ALDH1A1 | |
| SCHEMBL3824969 | 0.73 | MEN1 (0.59) | KMT2AL3MBTL1RAB9AMEN1ALDH1A1 | |
| SCHEMBL31078505 | 0.71 | HTR1B (0.49) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL4106875 | 0.71 | MEN1 (0.52) | KMT2AL3MBTL1RAB9AMEN1CYP1A2 | |
| SCHEMBL10451424 | 0.69 | BCAT2 (0.43) | KMT2AL3MBTL1RAB9AMEN1CYP1A2 | |
| SCHEMBL29915268 | 0.69 | MAOB (0.57) | L3MBTL1ALDH1A1GAAKDM4E | |
| SCHEMBL13543220 | 0.69 | KMT2A (0.64) | KMT2AL3MBTL1RAB9AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |