Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079070 | 0.83 | CYP19A1 (0.37) | AKR1B1CACNA1FALDH1A1MAPTCYP2C9 | |
| SCHEMBL14101183 | 0.82 | CYP2C9 (0.53) | AKR1B1CACNA1FALDH1A1MAPTCYP2C9 | |
| SCHEMBL1968442 | 0.79 | TSHR (0.48) | AKR1B1AKR1A1MMP13MMP2MMP9 | |
| SCHEMBL27224364 | 0.72 | CYP2C9 (0.64) | AKR1B1AKR1A1CACNA1FALDH1A1MAPT | |
| SCHEMBL204119 | 0.69 | LMNA (0.51) | AKR1B1MMP13CACNA1FALDH1A1MAPT | |
| SCHEMBL4385865 | 0.69 | LMNA (0.51) | AKR1B1MMP13CACNA1FALDH1A1MAPT | |
| SCHEMBL6135313 | 0.69 | LMNA (0.51) | AKR1B1MMP13CACNA1FALDH1A1MAPT | |
| SCHEMBL31078922 | 0.67 | SCN4A (0.47) | ALDH1A1MAPTCYP2C9SCN4ABLM | |
| SCHEMBL10521989 | 0.67 | CYP2C9 (0.79) | AKR1B1AKR1A1CACNA1FALDH1A1MAPT | |
| SCHEMBL14581598 | 0.66 | CA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |