Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | FASN | P49327 | 1/20 | 0.74 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954259 | 1.00 | POLB (0.74) | POLBFASNKAT2APAOXABHD16A | |
| SCHEMBL31079521 | 1.00 | POLB (0.74) | POLBFASNKAT2APAOXABHD16A | |
| SCHEMBL3007085 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL360509 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| Protolichesterinic Acid SCHEMBL7913878 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL7920753 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL13193435 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL7920757 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL17787714 | 0.85 | POLB (1.00) | POLBFASNKAT2A | |
| SCHEMBL6428922 | 0.85 | POLB (1.00) | POLBFASNKAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | POLB 3393/4885FASN 499/4885KAT2A 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.