Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23243185 | 1.00 | ALOX15 (0.45) | ALOX15HPGDCA12CA1CA2 | |
| SCHEMBL5596357 | 0.80 | CYP1A2 (0.41) | HPGDMAPK1CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL23781932 | 0.78 | MAPK14 (0.43) | HPGDMAPK14ALDH1A1 | |
| SCHEMBL2248029 | 0.78 | ALOX15 (0.43) | ALOX15HPGDCA12CA1CA2 | |
| SCHEMBL31080125 | 0.77 | GAA (0.46) | JAK2MEN1KMT2A | |
| SCHEMBL23243142 | 0.77 | GAA (0.46) | JAK2MEN1KMT2A | |
| SCHEMBL31470552 | 0.77 | KDM4E (0.50) | ALOX15HPGDPOLBMAPK1ALDH1A1 | |
| SCHEMBL38663775 | 0.77 | KDM4E (0.50) | ALOX15HPGDPOLBMAPK1ALDH1A1 | |
| SCHEMBL17979932 | 0.77 | ALOX15 (0.50) | ALOX15HPGDCA12CA1CA2 | |
| SCHEMBL31079860 | 0.77 | ALOX15 (0.50) | ALOX15HPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |