SCHEMBL23243185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31079696	1.00	ALOX15 (0.45)	ALOX15HPGDCA12CA1CA2
	SCHEMBL5596357	0.80	CYP1A2 (0.41)	HPGDMAPK1CYP2C9ALDH1A1HSD17B10
	SCHEMBL23781932	0.78	MAPK14 (0.43)	HPGDMAPK14ALDH1A1
	SCHEMBL2248029	0.78	ALOX15 (0.43)	ALOX15HPGDCA12CA1CA2
	SCHEMBL31080125	0.77	GAA (0.46)	JAK2MEN1KMT2A
	SCHEMBL23243142	0.77	GAA (0.46)	JAK2MEN1KMT2A
	SCHEMBL31470552	0.77	KDM4E (0.50)	ALOX15HPGDPOLBMAPK1ALDH1A1
	SCHEMBL38663775	0.77	KDM4E (0.50)	ALOX15HPGDPOLBMAPK1ALDH1A1
	SCHEMBL17979932	0.77	ALOX15 (0.50)	ALOX15HPGDCA12CA1CA2
	SCHEMBL31079860	0.77	ALOX15 (0.50)	ALOX15HPGDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.