Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18990453 | 1.00 | AAK1 (0.45) | AAK1SUCNR1GPR88LATS1ROCK2 | |
| SCHEMBL18990450 | 1.00 | AAK1 (0.45) | AAK1SUCNR1GPR88LATS1ROCK2 | |
| SCHEMBL29357190 | 0.92 | AAK1 (0.45) | AAK1GPR88LATS1ROCK2ROCK1 | |
| SCHEMBL18990566 | 0.77 | SUCNR1 (0.47) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL18990569 | 0.77 | SUCNR1 (0.47) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL29357754 | 0.76 | GPR88 (0.41) | SUCNR1GPR88LATS1CA12CA1 | |
| SCHEMBL31080074 | 0.76 | SUCNR1 (0.43) | SUCNR1GPR88CA12CA1CA2 | |
| SCHEMBL17784777 | 0.76 | STK17B (0.48) | LATS1ALOX5APMALT1 | |
| SCHEMBL23640753 | 0.74 | KDM4D (0.58) | LATS1CA12CA1CA2CA9 | |
| SCHEMBL17310202 | 0.74 | DYRK1A (0.49) | LATS1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368040-B | Diaryl monocyclic beta-lactam compounds and methods for their use in the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |