Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354779 | 1.00 | GPR88 (0.40) | GPR88MALT1SUCNR1BCHECKS1B | |
| SCHEMBL18991830 | 0.89 | KDM4E (0.36) | KDM4EALDH1A1PRMT5TSHRHTT | |
| SCHEMBL29357754 | 0.83 | GPR88 (0.41) | GPR88MALT1SUCNR1BCHECA12 | |
| SCHEMBL29357817 | 0.76 | MALT1 (0.43) | GPR88MALT1SUCNR1BCHECKS1B | |
| SCHEMBL18990553 | 0.73 | CA12 (0.41) | MALT1SUCNR1BCHECKS1BSKP1 | |
| SCHEMBL31079965 | 0.73 | CA12 (0.41) | MALT1SUCNR1BCHECKS1BSKP1 | |
| SCHEMBL18990554 | 0.73 | CA12 (0.41) | MALT1SUCNR1BCHECKS1BSKP1 | |
| SCHEMBL18991113 | 0.72 | MALT1 (0.41) | MALT1BCHECKS1BSKP1SKP2 | |
| SCHEMBL18990935 | 0.72 | LMNA (0.41) | PRMT5LMNA | |
| SCHEMBL18990453 | 0.71 | AAK1 (0.45) | GPR88MALT1SUCNR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368040-B | Diaryl monocyclic beta-lactam compounds and methods for their use in the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |