SCHEMBL31082238

SCHEMBL31082238

CC(C)(C)OC(=O)N(C1CC1)C1CCN(c2ccc(C(N)=O)c3ncncc23)CC1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ RPS6KB1 P23443 20/20 0.56
▸ AKT1 P31749 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31082451 0.91 RPS6KB1 (0.47) RPS6KB1AKT1
SCHEMBL31082602 0.90 RPS6KB1 (0.46) RPS6KB1AKT1
SCHEMBL31082620 0.87 GPR119 (0.44) RPS6KB1AKT1
SCHEMBL31082483 0.84 GPR119 (0.43) RPS6KB1AKT1
SCHEMBL31210701 0.82 GPR119 (0.39) RPS6KB1AKT1
SCHEMBL31082867 0.82 GPR119 (0.39) RPS6KB1AKT1
SCHEMBL31082980 0.81 GPR119 (0.46) RPS6KB1
SCHEMBL31082296 0.80 GPR119 (0.40) RPS6KB1
SCHEMBL31082538 0.76 GPR119 (0.44) RPS6KB1
SCHEMBL31082683 0.75 GPR119 (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024182788-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2024-09-06 — — WO disclosed
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