SCHEMBL31082483

SCHEMBL31082483

COc1ncc2c(N3CCC(N(C(=O)OC(C)(C)C)C4CC4)CC3)ccc(C(N)=O)c2n1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 3/20 0.43
▸ RPS6KB1 P23443 17/20 0.43
▸ AKT1 P31749 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31082538 0.92 GPR119 (0.44) GPR119RPS6KB1
SCHEMBL31082489 0.91 GPR119 (0.43) GPR119RPS6KB1
SCHEMBL31082343 0.87 GPR119 (0.44) GPR119
SCHEMBL31082778 0.87 GPR119 (0.44) GPR119
SCHEMBL31082296 0.87 GPR119 (0.40) GPR119RPS6KB1
SCHEMBL31082238 0.84 RPS6KB1 (0.56) RPS6KB1AKT1
SCHEMBL31082842 0.81 GPR119 (0.46) GPR119
SCHEMBL31210701 0.80 GPR119 (0.39) GPR119RPS6KB1AKT1
SCHEMBL31082867 0.80 GPR119 (0.39) GPR119RPS6KB1AKT1
SCHEMBL31082601 0.79 GPR119 (0.41) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024182788-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2024-09-06 — — WO disclosed
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