SCHEMBL31083458

SCHEMBL31083458

COc1cc2c(cc1F)CCCN2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
ATM Q13315 1/20 0.38
TLR9 Q9NR96 1/20 0.38
TLR8 Q9NR97 1/20 0.38
TLR7 Q9NYK1 1/20 0.38
AR P10275 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31083497 0.93 MAPT (0.41) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL10912768 0.86 MAPT (0.45) GAAKDM4EMAPTALDH1A1LMNA
Hydrochloric Acid SCHEMBL7373928 0.84 MAPT (0.44) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL30340758 0.81 MAPT (0.43) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL5468971 0.81 MAPT (0.43) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL25405400 0.80 HTR2C (0.47) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL18122551 0.80 HTR2C (0.56) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL30480865 0.80 HTR2C (0.56) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL4788966 0.80 HTR2A (0.43) GAAKDM4EMAPTALDH1A1LMNA
SCHEMBL2217869 0.80 MAPT (0.45) GAAKDM4EMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
WO-2024213650-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed