Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912768 | 0.86 | MAPT (0.45) | HTR2AHTR2CHTR2BATMTLR9 | |
| Hydrochloric Acid SCHEMBL7373928 | 0.84 | MAPT (0.44) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL5468971 | 0.81 | MAPT (0.43) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL30340758 | 0.81 | MAPT (0.43) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL25405400 | 0.80 | HTR2C (0.47) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL18122551 | 0.80 | HTR2C (0.56) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL31083458 | 0.80 | GAA (0.41) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL30480865 | 0.80 | HTR2C (0.56) | HTR2AHTR2CHTR2BATMTLR9 | |
| SCHEMBL21468538 | 0.77 | L3MBTL1 (0.39) | ATMTLR9TLR8TLR7KDM4E | |
| SCHEMBL31083497 | 0.77 | MAPT (0.41) | HTR2AHTR2CHTR2BATMTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2012058125-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |