Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 17/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25606380 | 1.00 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| SCHEMBL30678886 | 0.96 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| SCHEMBL14751855 | 0.82 | PIK3CA (0.36) | PIK3R1PIK3CA | |
| SCHEMBL31158263 | 0.82 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| Nerandomilast SCHEMBL14734178 | 0.81 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| Nerandomilast SCHEMBL25606332 | 0.81 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| SCHEMBL30708580 | 0.80 | PIK3CA (0.35) | PIK3R1PIK3CA | |
| SCHEMBL30678851 | 0.80 | PIK3R1 (0.33) | PIK3R1PIK3CA | |
| SCHEMBL30639352 | 0.80 | — | — | |
| SCHEMBL15996321 | 0.79 | KMT2A (0.37) | PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674852-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | Innovstone Therapeutics Limited (CN) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179493-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | 上海翊石医药科技有限公司 | 2024-09-06 | — | — | WO | disclosed |