Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 18/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14751855 | 0.82 | PIK3CA (0.36) | PIK3CAPIK3R1PIK3CDPIK3CB | |
| SCHEMBL30678886 | 0.81 | PIK3R1 (0.34) | PIK3CAPIK3R1 | |
| SCHEMBL25606380 | 0.80 | PIK3R1 (0.34) | PIK3CAPIK3R1 | |
| SCHEMBL31084092 | 0.80 | PIK3R1 (0.34) | PIK3CAPIK3R1 | |
| SCHEMBL31158263 | 0.80 | PIK3R1 (0.34) | PIK3CAPIK3R1 | |
| SCHEMBL31571886 | 0.80 | HSD11B1 (0.31) | — | |
| SCHEMBL30678851 | 0.80 | PIK3R1 (0.33) | PIK3CAPIK3R1 | |
| SCHEMBL373572 | 0.79 | GRM5 (0.34) | PIK3CAPIK3R1 | |
| SCHEMBL31571857 | 0.79 | PDE4B (0.30) | — | |
| Nerandomilast SCHEMBL14734178 | 0.79 | PIK3R1 (0.34) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092985-A1 | PHOSPHODIESTERASE 4B INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 合肥医工医药股份有限公司 | 2025-05-08 | — | — | WO | disclosed |
| WO-2023241683-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND ACTING AS PDE4B INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-12-21 | — | — | WO | disclosed |