Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.71 |
| ▸ | RELA | Q04206 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134094 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL25239669 | 0.86 | MAPT (0.81) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7369499 | 0.82 | MAPT (0.54) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL3593375 | 0.81 | MEN1 (0.57) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL427925 | 0.80 | MEN1 (0.75) | MAPTSMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL8357836 | 0.80 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL25279844 | 0.80 | RAB9A (0.59) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL12190708 | 0.79 | RAB9A (0.59) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL25288808 | 0.79 | RAB9A (0.73) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| Bromide SCHEMBL8360766 | 0.79 | NPC1 (0.73) | MAPTSMN1; SMN2NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574812-A | Benzenesulfonamide thiazole compounds and their use for the treatment of cancer | 国家医疗保健研究所 | 2024-08-30 | — | — | CN | disclosed |