Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655814 | 1.00 | CSNK2A1 (0.46) | CSNK2A1AHRESR1NPC1RAB9A | |
| SCHEMBL5148081 | 0.78 | ALDH1A1 (0.47) | CSNK2A1AHRNPC1RAB9AGPR84 | |
| SCHEMBL22655893 | 0.77 | CDC7 (0.53) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL31085390 | 0.77 | CDC7 (0.53) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL28306668 | 0.76 | AHR (0.63) | AHRESR1NPC1RAB9AGPR84 | |
| SCHEMBL17539398 | 0.73 | SCN9A (0.42) | CSNK2A1PRKCQPRKCDSYKEGFR | |
| SCHEMBL15379850 | 0.71 | TDP1 (0.48) | PRKCQPRKCDMEN1PRKD3EGFR | |
| SCHEMBL15380326 | 0.71 | MAPT (0.46) | NPC1RAB9APRKCQPRKCDMEN1 | |
| SCHEMBL30593539 | 0.71 | GPR84 (0.69) | CSNK2A1AHRGPR84MEN1MAPT | |
| SCHEMBL1248842 | 0.71 | GPR84 (0.69) | CSNK2A1AHRGPR84MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114096542-B | Condensed tricyclic pyrroles as alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2024-09-10 | — | — | CN | disclosed |