Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 4/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255373 | 1.00 | NCOA1 (0.35) | NCOA1NCOA3S1PR1S1PR3KCNQ3 | |
| SCHEMBL29255096 | 0.90 | LTA4H (0.44) | S1PR1S1PR3LTA4HKCNH2PPARG | |
| SCHEMBL31086430 | 0.90 | LTA4H (0.44) | S1PR1S1PR3LTA4HKCNH2PPARG | |
| SCHEMBL29255261 | 0.87 | SCN9A (0.39) | LTA4HSCN9AKCNH2MAPTACACB | |
| SCHEMBL31086532 | 0.85 | LTA4H (0.42) | LTA4HSCN9AKCNH2GAAKDM4E | |
| SCHEMBL29254800 | 0.85 | LTA4H (0.42) | LTA4HSCN9AKCNH2GAAKDM4E | |
| SCHEMBL29254835 | 0.84 | LTA4H (0.41) | S1PR1S1PR3LTA4HSCN9AKCNH2 | |
| SCHEMBL31086470 | 0.84 | PPARG (0.39) | S1PR1S1PR3LTA4HSCN9AKCNH2 | |
| SCHEMBL29255220 | 0.84 | PPARG (0.39) | S1PR1S1PR3LTA4HSCN9AKCNH2 | |
| SCHEMBL29254708 | 0.83 | PPARG (0.38) | S1PR1S1PR3LTA4HSCN9AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |