Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254800 | 0.90 | LTA4H (0.42) | SCN9ALTA4HKCNH2PTGER4MET | |
| SCHEMBL31086532 | 0.90 | LTA4H (0.42) | SCN9ALTA4HKCNH2PTGER4MET | |
| SCHEMBL29255373 | 0.87 | NCOA1 (0.35) | SCN9ALTA4HKCNH2MEN1MAPT | |
| SCHEMBL31086367 | 0.87 | NCOA1 (0.35) | SCN9ALTA4HKCNH2MEN1MAPT | |
| SCHEMBL29255223 | 0.82 | PPARG (0.42) | LTA4HKCNH2MEN1MAPTKMT2A | |
| SCHEMBL29254756 | 0.81 | LMNA (0.42) | SCN9ALTA4HKCNH2MEN1MAPT | |
| SCHEMBL29255043 | 0.80 | LTA4H (0.46) | LTA4HKCNH2MAPTPPARGLMNA | |
| SCHEMBL29254835 | 0.80 | LTA4H (0.41) | SCN9ALTA4HKCNH2MAPTACACB | |
| SCHEMBL29254797 | 0.79 | SCN9A (0.38) | SCN9ALTA4HKCNH2PTGER4MET | |
| SCHEMBL29255225 | 0.79 | MIF (0.46) | MEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |