Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966615 | 1.00 | TP53 (0.68) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL8819152 | 0.87 | KDM4D (0.68) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL22983344 | 0.86 | TP53 (0.77) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL7287487 | 0.85 | SIRT2 (0.76) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL6001715 | 0.83 | POLB (0.68) | TP53HTTALDH1A1L3MBTL1LMNA | |
| SCHEMBL15233661 | 0.82 | POLB (0.62) | TP53HTTALDH1A1HDAC3HDAC1 | |
| SCHEMBL2330387 | 0.82 | ALDH1A1 (0.73) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL14880379 | 0.81 | PKM (0.79) | TP53MAPTSIRT2RXFP1TDP1 | |
| SCHEMBL1520536 | 0.80 | HDAC1 (0.70) | TP53HTTALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL2339343 | 0.79 | ALDH1A1 (1.00) | TP53HTTALDH1A1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459438-A | Synthesis method of iodine-catalyzed N-acyl-2-hydroxy-indol-3-one compound | 延安大学 | 2024-08-09 | — | — | CN | disclosed |