Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343169 | 0.78 | DYRK1A (0.42) | DYRK1ATLR8MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7911284 | 0.71 | — | — | |
| SCHEMBL29951766 | 0.71 | — | — | |
| SCHEMBL769669 | 0.70 | DYRK1A (0.46) | DYRK1ATLR8L3MBTL1ALDH1A1MAPT | |
| SCHEMBL16955465 | 0.68 | ALDH1A1 (0.37) | DYRK1ATLR8MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL584047 | 0.68 | CYP1A2 (0.50) | DYRK1ATLR8ALDH1A1MAPTKDM4E | |
| SCHEMBL5875840 | 0.68 | ALDH1A1 (0.41) | DYRK1ATLR8L3MBTL1ALDH1A1MAPT | |
| SCHEMBL9329818 | 0.68 | L3MBTL1 (0.47) | DYRK1AL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL619229 | 0.68 | ALDH1A1 (0.36) | DYRK1ATLR8ALDH1A1MAPTKDM4E | |
| SCHEMBL17541429 | 0.68 | DYRK1A (0.40) | DYRK1ATLR8MAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | claimed |
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | disclosed |