Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 9/20 | 0.44 |
| ▸ | CNR1 | P21554 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31626860 | 0.79 | OXER1 (0.45) | OXER1CNR2CNR1KDM4EPPARA | |
| SCHEMBL3007779 | 0.77 | TRPA1 (0.45) | OXER1CNR2CNR1KDM4ETRPA1 | |
| SCHEMBL3004060 | 0.77 | TRPA1 (0.45) | OXER1CNR2CNR1KDM4ETRPA1 | |
| SCHEMBL9222284 | 0.77 | ALDH1A1 (0.42) | OXER1CNR1KDM4EPPARAPPARG | |
| SCHEMBL9222289 | 0.77 | ALDH1A1 (0.42) | OXER1CNR1KDM4EPPARAPPARG | |
| SCHEMBL3004063 | 0.77 | TRPA1 (0.45) | OXER1CNR2CNR1KDM4ETRPA1 | |
| SCHEMBL13469394 | 0.76 | CNR2 (0.56) | CNR2CNR1KDM4EPPARAPPARG | |
| SCHEMBL15291032 | 0.76 | CNR2 (0.56) | CNR2CNR1KDM4EPPARAPPARG | |
| SCHEMBL13469404 | 0.76 | CNR2 (0.56) | CNR2CNR1KDM4EPPARAPPARG | |
| SCHEMBL6941510 | 0.76 | KDM4E (0.51) | OXER1CNR2CNR1KDM4EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028348-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20250333429-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12384808-B2 | Modulators of TNF-α activity | FORWARD THERAPEUTICS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20240247014-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384808-B2 | Modulators of TNF-α activity | TNF, NFKBIA, TNFRSF1A | OXER1 2708/4885CNR2 4641/4885CNR1 4501/4885 |
| US-20250333429-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | TNF, NFKBIA, TNFRSF1A | OXER1 2786/4885CNR2 4653/4885CNR1 4491/4885 |
| US-20260028348-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | TNF, TNFRSF1A, TNFRSF9 | OXER1 365/4885CNR2 1067/4885CNR1 745/4885 |
| US-20240247014-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | TNF, NFKBIA, TNFRSF1A | OXER1 2786/4885CNR2 4653/4885CNR1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.