Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545242 | 0.98 | KDM4E (0.41) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL27300102 | 0.92 | GAA (0.43) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL31089194 | 0.84 | TSHR (0.41) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL27497690 | 0.83 | KDM4E (0.45) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL9796453 | 0.82 | KDM4E (0.40) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL6544313 | 0.80 | KDM4E (0.39) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL28567972 | 0.79 | CYP3A4 (0.35) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL6545234 | 0.79 | CYP3A4 (0.35) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL14559645 | 0.77 | GAA (0.36) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL6545165 | 0.77 | ALDH1A1 (0.38) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |