Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27300102 | 0.88 | GAA (0.43) | LMNAALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL6023769 | 0.85 | TSHR (0.40) | TSHRLMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL31088807 | 0.84 | GAA (0.40) | LMNAALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL6545242 | 0.83 | KDM4E (0.41) | TSHRALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL24906928 | 0.79 | ALDH1A1 (0.47) | TSHRLMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL8146725 | 0.79 | TSHR (0.45) | TSHRLMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL27497690 | 0.79 | KDM4E (0.45) | LMNAALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL16268204 | 0.77 | TSHR (0.44) | TSHRLMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2085077 | 0.77 | TSHR (0.44) | TSHRLMNAPOLBALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16268518 | 0.76 | TSHR (0.42) | TSHRLMNAPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |