Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 5/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 4/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.37 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24165519 | 0.84 | HDAC3 (0.40) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL31089879 | 0.83 | PDPK1 (0.35) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL24165525 | 0.83 | DCTPP1 (0.39) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL15661963 | 0.82 | PDPK1 (0.38) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL24166208 | 0.82 | ERN1 (0.42) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL1156790 | 0.79 | ERN1 (0.39) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL1354815 | 0.79 | CDK2 (0.39) | CDK2CCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL21470471 | 0.78 | FGFR1 (0.42) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL17289609 | 0.78 | PDPK1 (0.40) | PDPK1FGFR1WNT1GSK3BDYRK1A | |
| SCHEMBL31089900 | 0.78 | WNT1 (0.36) | PDPK1WNT1GSK3BDYRK1ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300948-A1 | Heterocyclic Compounds As Kinase Inhibitors | INCYTE CORPORATION | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300948-A1 | Heterocyclic Compounds As Kinase Inhibitors | JAK2, JAK1, JAK3 | PDPK1 123/4885FGFR1 523/4885WNT1 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.