Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.36 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.36 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.36 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.36 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096698 | 0.95 | FAP (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3110169 | 0.92 | FAP (0.33) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3104661 | 0.91 | FAP (0.35) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3115082 | 0.91 | TP53 (0.33) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3097102 | 0.90 | GPR139 (0.41) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3641457 | 0.90 | HTT (0.35) | FAPDRD3 | |
| SCHEMBL3105459 | 0.89 | CCR1 (0.31) | TACR1 | |
| SCHEMBL3113510 | 0.88 | CA1 (0.30) | — | |
| SCHEMBL3104839 | 0.87 | GPR139 (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3105544 | 0.87 | FAP (0.35) | PSMB11PSMA7PSMB1PSMA1PSMA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222618-A1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2017-09-27 | — | — | EP | claimed |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2014-04-24 | — | — | US | claimed |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | DU PONT (US) | 2013-08-22 | — | — | US | claimed |
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | claimed |
| EP-3222618-B1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3222618-A1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2014-04-24 | — | — | US | disclosed |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | DU PONT (US) | 2013-08-22 | — | — | US | disclosed |
| US-8410153-B2 | Naphthalene isoxazoline invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2158188-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. Du Pont de Nemours and Company (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2009002809-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | C1S, C1R, C9 | PSMB11 616/4885PSMA7 1611/4885PSMB1 353/4885 |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | PSMB11 616/4885PSMA7 1611/4885PSMB1 353/4885 |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | PSMB11 616/4885PSMA7 1611/4885PSMB1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.