SCHEMBL31092003

SCHEMBL31092003

C[Si](C)(C)CCOCn1ncc2nc(C(F)(F)F)cc(C=O)c21

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31092009 0.89 DGAT1 (0.39) DGAT1
SCHEMBL31092001 0.84 DGAT1 (0.41) DGAT1
SCHEMBL2425423 0.81 DGAT1 (0.35) DGAT1
SCHEMBL2430654 0.78 DGAT1 (0.37) DGAT1
SCHEMBL35211435 0.75 DGAT1 (0.46) DGAT1
SCHEMBL35211150 0.75 DGAT1 (0.41) DGAT1
SCHEMBL2430468 0.75 DGAT1 (0.37) DGAT1
SCHEMBL2426778 0.75 DGAT1 (0.33) DGAT1
SCHEMBL29640102 0.75 DGAT1 (0.45) DGAT1
SCHEMBL2428441 0.74 DGAT1 (0.34) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450271-B Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2024-09-20 CN disclosed