Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092009 | 0.84 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL31092003 | 0.84 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL35211150 | 0.83 | DGAT1 (0.41) | DGAT1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL35211435 | 0.79 | DGAT1 (0.46) | DGAT1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29640102 | 0.78 | DGAT1 (0.45) | DGAT1GRIN2B | |
| SCHEMBL31138676 | 0.77 | TUBB4A (0.32) | DGAT1MAPT | |
| SCHEMBL29640162 | 0.77 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL29937160 | 0.76 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL26720196 | 0.75 | ATR (0.33) | DGAT1MAPTGRIN2B | |
| SCHEMBL18188410 | 0.74 | HTR2A (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |