Decussatin

Decussatin

SCHEMBL31093409

COc1cc(O)c2c(=O)c3c(OC)c(OC)ccc3oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 1.00
MGAM O43451 7/20 0.82
KDM4E B2RXH2 1/20 0.80
ALDH1A1 P00352 1/20 0.80
LMNA P02545 1/20 0.80
MAPT P10636 1/20 0.80
HPGD P15428 1/20 0.80
GAA P10253 1/20 0.71
SI P14410 1/20 0.71
MGAM2 Q2M2H8 1/20 0.71
ABCG2 Q9UNQ0 4/20 0.68
ABCB1 P08183 2/20 0.68
ABCC1 P33527 2/20 0.68
DPP4 P27487 1/20 0.59
XDH P47989 1/20 0.59
PLG P00747 1/20 0.57
NOX4 Q9NPH5 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decussatin SCHEMBL15918485 1.00 MAOA (1.00) MAOAMGAMKDM4EALDH1A1LMNA
Decussatin SCHEMBL30061117 1.00 MAOA (1.00) MAOAMGAMKDM4EALDH1A1LMNA
Getiacaulein SCHEMBL27728392 0.89 KDM4E (1.00) MAOAMGAMKDM4EALDH1A1LMNA
SCHEMBL18240046 0.88 MGAM (0.82) MAOAMGAMKDM4EALDH1A1LMNA
SCHEMBL29473310 0.84 MAOA (0.72) MAOAMGAMKDM4EALDH1A1LMNA
SCHEMBL7933844 0.83 MAOA (0.72) MAOAMGAMKDM4EALDH1A1LMNA
SCHEMBL27979675 0.82 MGAM (1.00) MAOAMGAMKDM4EALDH1A1LMNA
Gentiakochianin SCHEMBL29894101 0.82 MGAM (1.00) MAOAMGAMKDM4EALDH1A1LMNA
Retusin SCHEMBL1421755 0.81 ABCG2 (1.00) MAOAKDM4EALDH1A1LMNAMAPT
Retusin SCHEMBL29496204 0.81 ABCG2 (1.00) MAOAKDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118557626-A Application of costal flower extract in preparation of medicines for treating hepatic fibrosis 内蒙古民族大学 2024-08-30 CN disclosed