Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.72 |
| ▸ | MGAM | O43451 | 5/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334427 | 0.91 | MGAM (0.70) | MAOAMGAMACHEMAOBABCB1 | |
| SCHEMBL4785647 | 0.90 | MAOA (0.70) | MAOAMGAMACHEMAOBABCG2 | |
| SCHEMBL15918251 | 0.86 | MAOA (0.66) | MAOAMGAMACHEMAOBABCG2 | |
| SCHEMBL27734348 | 0.85 | MAOA (0.65) | MAOAMGAMACHEMAOBABCG2 | |
| SCHEMBL30786761 | 0.85 | MAOA (0.65) | MAOAMGAMACHEMAOBABCG2 | |
| SCHEMBL7931361 | 0.84 | MAOA (1.00) | MAOAMGAMACHEMAOBKDM4E | |
| Decussatin SCHEMBL30061117 | 0.83 | MAOA (1.00) | MAOAMGAMABCG2ABCB1ABCC1 | |
| Decussatin SCHEMBL15918485 | 0.83 | MAOA (1.00) | MAOAMGAMABCG2ABCB1ABCC1 | |
| Decussatin SCHEMBL31093409 | 0.83 | MAOA (1.00) | MAOAMGAMABCG2ABCB1ABCC1 | |
| SCHEMBL27979675 | 0.82 | MGAM (1.00) | MAOAMGAMACHEMAOBABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6224906-B1 | STABLE, FREE-FLOWING POWDER | NATREON INC. | 2001-05-01 | — | — | US | disclosed |