Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513879 | 1.00 | RAB9A (0.50) | RAB9ANPC1AURKBSMN1; SMN2PKM | |
| SCHEMBL1284289 | 0.76 | PDE4B (0.58) | RAB9AAURKBSMN1; SMN2MAPTADORA2A | |
| SCHEMBL10639656 | 0.73 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL29549332 | 0.72 | ADORA2A (0.43) | RAB9AGAAALDH1A1MAPTADORA2A | |
| SCHEMBL22828480 | 0.72 | ADORA2A (0.43) | RAB9AGAAALDH1A1MAPTADORA2A | |
| SCHEMBL1283919 | 0.72 | ADORA2A (0.47) | RAB9ANPC1SMN1; SMN2GAAMAPT | |
| SCHEMBL20589378 | 0.72 | ADORA2A (0.52) | AURKBADORA2AADORA1PDE4APDE4B | |
| SCHEMBL20589377 | 0.72 | ADORA2A (0.52) | AURKBADORA2AADORA1PDE4APDE4B | |
| SCHEMBL31095355 | 0.72 | ADORA2A (0.52) | AURKBADORA2AADORA1PDE4APDE4B | |
| SCHEMBL15022003 | 0.72 | RAB9A (0.78) | RAB9ANPC1SMN1; SMN2PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |